Post-operative avoidance of radiotherapy in minimal risk women: patient selection using biomarkers

This study is to see if women who only have a very small risk of their breast cancer returning need to have radiotherapy after surgery. 


Radiotherapy reduces the risk of the cancer coming back in the breast (local recurrence). But radiotherapy has side effects. For women who only have a very small chance of their cancer coming back, the side effects of radiotherapy could outweigh the benefits.


In this study researchers do an extra test on the sample already taken from a biopsy  This is called a Ki67 test. The result of the Ki67 test is used with other routine test results and information about the type of breast cancer. From this the researchers can create a score which can show who might be at a:

  • low risk of their cancer coming back
  • very low risk of their cancer coming back

This score is called the IHC4+C score.


The study aims to find out:

  • which women are at very low risk of their breast cancer coming back
  • if these women can avoid having radiotherapy treatment

Further details at - CRUK or Association of Breast Surgery


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2017 Summer School

The 2017 ICPV Summer School was held over two days in June at Stirling University. The theme of the event was Cancer Survivorship and Living Well Cancer. Click below for details of the course. More details.

VOICE 2016

A snapsot video of the the 2016 course is now available on YouTube VOICE2016

eCancer Videos

At the BACR/ECMC conference in July Maggie Wilcox and Mairead Mackenzie were persuaded to speak to the camera. Maggie gave a background to ICPV and our aims and objectives. While Mairead focused on her specific interests and activities. To view follow the links below.

Maggie Wilcox

Mairead MacKenzie

July 2016 Conferences

ICPV members were busy this week with two conferences. The BACR/ECMC Joint Meeting on Therapeutic Interventions for Cancer Prevention was held in Bristol July18-19. The UK Breast Cancer Research Symposium was held in London from July 22-23. Click here for more information.

UK Therapeutic Cancer Prevention Network (UKTCPN)

An update from this new group was presented to the ECMC Annual Network Meeting in May 2016. Click here to download and read. 


Call for immediate change to European Paediatric Medicine Regulation to save more lives of children and teens with cancer.
A few basic changes to European Law could speed up access to newer, kinder and potentially better drugs for more children and teenagers with cancer. Click to Sign the petition 


Two years on from the start pioneering TRACERx lung cancer study. Click here For the latest news and patient views on this study. 

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