POETIC

This trial is looking at whether having hormone therapy for 2 weeks before and 2 weeks after surgery helps postmenopausal women with breast cancer. The trial is supported by Cancer Research UK.

The first treatment for early breast cancer is usually surgery. After surgery, women who have hormone receptor positive breast cancer will have hormone therapy as part of their treatment. Most women have hormone therapy for at least 5 years. This helps to reduce the risk of breast cancer coming back.

Drugs called aromatase inhibitors are a type of hormone therapy for women who have gone through the menopause. In this trial, doctors want to find out if having an aromatase inhibitor for 2 weeks before and after surgery, as well as standard hormone therapy, helps reduce the risk of breast cancer coming back even more.

The researchers will also look at testing the cancer cells to see if there are any changes after a short course of hormone therapy. In the future, this may help doctors to work out which treatment is best for each individual patient. The aims of the trial are to

  • See if 4 weeks of an aromatase inhibitor at the time of surgery helps to reduce the risk of early breast cancer coming back
  • Find out if testing the cancer cells after 2 weeks of hormone therapy can help to predict how well a woman will respond to treatment

 

For more information about this trial go to :

 

http://www.cancerresearchuk.org/cancer-help/trials/a-trial-of-a-short-course-of-hormone-therapy-before-and-after-surgery-for-early-breast-cancer

 

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Maggie Wilcox

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